Vseživljenjski odtis nosečnosti – vpliv prenatalnega stresa na otrokov duševni in čustveni razvoj

Mrak, Monika (avtor), Mivšek, Ana Polona (mentor)

Uvod: Otrok je v času razvoja v maternici zelo dovzeten za škodljive vplive iz okolja. Med te škodljive dejavnike sodi stres, ki jev času nosečnosti odgovoren za povečano tveganje za nastanek čustvenih stisk pri še nerojenem otroku. Izpostavljenost stresu vpliva na razvoj in organizacijo živčnega sistema. Posledice prenatalnega stresa so motnje avtističnega spektra, hiperaktivnostne in pozornostne motnje, shizofrenija, čustvene in vedenjske motnje, depresivne in anksioznostne motnje. Namen: Pregledati zadnje, na dokazih temelječe študije, ki prikazujejo najnovejše rezultate s področja prenatalnega maternalnega stresa in njegovega vpliva na plod ter posledic, ki so prisotne kasneje v življenju posameznika. Metode dela:Uporabljena je bila deskriptivna ali opisna metoda dela s sistematičnim pregledom, oceno in analizo tujeter domače znanstvene in strokovne literature. Podatki so bili združeni in obdelani po principu meta-sinteze. Literatura je bila najdena s pomočjo združevalnega iskalnika DiKUL ter baz podatkov Cinahl, Medline, ScienceDirect, Pediatric Research, PubMed. Izbor zadetkov je bil omejen na izborne kriterije: starost članka, dostopnost celotnega besedila, vsebinska ustreznost vira, namen proučevanja, v slovenskem in angleškem jeziku. Rezultati: Otroci, ki so bili v času nosečnosti izpostavljeni stresu, imajo povišano količino kortizola v vzorcu sline, kar kaže na spremembe v razvoju živčevja in žlez z notranjim izločanjem. To sta dokazali dve metodološko močni študiji. 13 študij, od tega dve metodološko zelo močni, ostale pa so bile razvrščene v II. in III. kategorijo, so dokazale, da je izpostavljenost stresu v času nosečnosti dejavnik tveganja za razvoj hiperaktivnostnih motenj in motenj pozornosti, motenj avtističnega spektra, shizofrenije, depresije ter anksioznosti pri otroku kasneje v življenju. Prenatalni stres ima večji vpliv na moške potomce, ki so izpostavljeni stresu v drugi polovici nosečnosti. Mehanizmi delovanja in prenosa stresa še niso povsem jasni, raziskovalci pa poudarjajo pomen večjega števila metodološko močnih študij.

• Jezik: Slovenski jezik
• Ključne besede: prenatalni stres, razvoj ploda, kognitivni izidi, nevrološki razvoj
• Vrsta gradiva: Diplomsko delo/naloga
• Organizacija: ZF - Zdravstvena fakulteta
• Leto izida: 2017
• PID: 20.500.12556/RUL-91036
• COBISS.SI-ID: 5228651
• Datum objave v RUL: 13.03.2017

MRAK, Monika, 2017, Vseživljenjski odtis nosečnosti – vpliv prenatalnega stresa na otrokov duševni in čustveni razvoj [na spletu]. Diplomsko delo. [Dostopano 1 maj 2025]. Pridobljeno s: https://repozitorij.uni-lj.si/IzpisGradiva.php?lang=slv&id=91036

Sekundarni jezik

• Jezik: Angleški jezik
• Naslov: Lifelong imprint of pregnancy – effects of prenatal stress on child mental and emotional development

Izvleček

Introduction: The fetus is very susceptible to harmful environmental influences during the development in the womb. One of the harmful factors is stress. Stress during pregnancy is responsible for an increased risk of the development of emotional distress in a not-yet-born child. Exposure to stress affects the development and organisation of the nervous system. Consequences of prenatal stress are autism spectrum disorder, hyperactivity and attention deficit disorder, schizophrenia, emotional and behavioural disorders, depressive and anxiety disorders. Objective: To review the most recent evidence-based studies that present the latest results in the field of prenatal maternal stress and its effects on the fetus as well as the consequences present in later life of the individual. Methods: A descriptive research method with a systematic review, evaluation and analysis of foreign and domestic scientific and professional literature was used. The data were gathered and analysed according to the principles of meta-analysis. The literature was retrieved through federated search engine DiKUL and databases Cinahl, Medline, ScienceDirect, Pediatric Research, PubMed. The selection of hits was restricted to the selection criteria: article issue date, full text availability, contextual relevance of the source relative to the purpose of the study, the Slovene and the English language. Results: The children who were exposed to stress in-utero have an increased amount of cortisol in the saliva sample which indicates changes in the development of the nervous system and endocrine glands. It was demonstrated by two methodologically strong studies. Thirteen studies, two of which were methodologically very strong and the rest were classified in category II and III, proved that exposure to stress at the time of pregnancy is a risk factor for the development of hyperactivity and attention deficit disorders, autism spectrum disorder, schizophrenia, depression and anxiety in later life of the child. Prenatal stress has a greater influence on male offspring who are exposed to stress in the second half of the pregnancy. The mechanisms of action and transfer of stress are not yet entirely clear and researchers emphasise the importance of a larger number of methodologically strong studies.

• Ključne besede: prenatal stress, fetal development, cognitive outcomes, neurological development