Copper(II) is the most common oxidation state of copper in biological systems, which is why its coordination compounds are of considerable interest. In this master’s thesis, we modified the already known coordination compound [Cu(fur)2(CH3OH)2] (where fur– represents deprotonated furosemide) by replacing the methanol ligands with various heterocyclic amines, such as piperidine, pyrrolidine, morpholine and thiomorpholine, with the aim of investigating the effect of these changes. Different solvents, reaction conditions and reactant ratios were used.
Five copper(II) complexes with the general composition [Cu(fur)2(amine)2] were prepared. Both ligands coordinated in a monodentate manner. In the case of thiomorpholine, a coordination polymer was also formed. For all ligands except 2,6-dimethylmorpholine, unknown green compounds were also obtained. They were denoted as X_amine and were not successfully identified.
The resulting products were isolated and characterized by infrared spectroscopy (IR), UV–Vis spectroscopy, thermogravimetric analysis (TG), elemental analysis (CHN), and single-crystal X-ray diffraction analysis.
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