Immobilized and recyclable catalysts for deuterium labelling : recent developments and emerging strategies

Raju, Liju (avtor), Jedlovčnik, Luka (avtor), Košmrlj, Janez (avtor), Jansen-van Vuuren, Ross D. (avtor)

Deuterated compounds have become indispensable across a wide range of applications in medicinal chemistry and materials science, driving interest in the development of efficient and sustainable synthetic methodologies. In particular, there is a growing emphasis on greener approaches that enable deuteration under mild conditions which typically necessitate the use of catalytic systems. While homogeneous catalysts are often employed due to their high activity, their limited recoverability can lead to inefficiencies, waste generation, and potential product contamination. To address these challenges, increasing attention has been directed toward the use of immobilized and recyclable catalysts, which offer enhanced sustainability and operational advantages. Such systems not only facilitate catalyst recovery and reuse but also enable integration with continuous flow technologies, providing a promising route toward scalable and environmentally responsible deuteration processes. In this review, we survey recent advances (since June 2024) in the application of immobilized and recyclable catalysts for deuteration, with a focus on innovative materials, catalytic strategies, and emerging trends that are shaping the future of this field.

• Jezik: Angleški jezik
• Ključne besede: immobilized, suitable for recycling, catalyst, deuteration, continuous-flow chemistry, isotope exchange, deuterium labeling, carrier
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.02 - Pregledni znanstveni članek
• Organizacija: FKKT - Fakulteta za kemijo in kemijsko tehnologijo
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Leto izida: 2026
• Št. strani: Str. 3112-3146
• Številčenje: Vol. 4, iss. 8
• PID: 20.500.12556/RUL-182532
• UDK: 547.5:546.11.027*2:544.478
• ISSN pri članku: 2753-8125
• DOI: 10.1039/D6SU00003G
• COBISS.SI-ID: 277349379
• Datum objave v RUL: 15.05.2026

Gradivo je del revije

• Naslov: RSC sustainability
• Skrajšan naslov: RSC sustain.
• Založnik: Royal Society of Chemistry
• ISSN: 2753-8125
• COBISS.SI-ID: 175932931

Licence

• Licenca: CC BY 3.0, Creative Commons Priznanje avtorstva 3.0 Nedoločena
• Povezava: https://creativecommons.org/licenses/by/3.0/deed.sl
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Sekundarni jezik

• Jezik: Slovenski jezik
• Ključne besede: imobiliziran, primeren za recikliranje, katalizator, deuteriranje, kemija s kontinuiranim pretokom, izotopska izmenjava, označevanje z devterijem, nosilec