Drivers and potential effects of endocrine disruption in wild mammals : known facts and open questions

Karaer, Mina Cansu (avtor), Snoj, Tomaž (avtor)

Endocrine disruption has become a critical ecological problem, with environmental pollutants such as pesticides, industrial chemicals, and pharmaceutical residues playing crucial roles in altering endocrine regulation and disrupting key physiological processes. This overview addresses the mechanisms of endocrine disruption, focusing on how endocrine-disrupting chemicals (EDCs) interfere with hormone synthesis, receptor binding, and cellular signalling pathways, ultimately impacting animal reproductive function, development, and metabolism and thus affecting individuals, populations and ecosystems. We summarize the current state of knowledge on endocrine disruption and propose new research topics to clarify the effects of various substances with endocrine activity on organisms. Inter-species differences in sensitivity to EDCs, differences in receptor structure between species, observational studies on developmental disorders, effects of mixtures of EDCs, studies on epigenetic and transgenerational effects, and interactions between EDCs and other environmental stressors are presented as important topics for further research. Finally, we emphasize the need for collective action to protect biodiversity by curbing environmental pollution with EDCs.

• Jezik: Angleški jezik
• Ključne besede: ecosystems, endocrine disruption, endocrine-disrupting chemicals, metabolic disorders, reproductive disorders, wild mammals
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.02 - Pregledni znanstveni članek
• Organizacija: VF - Veterinarska fakulteta
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Leto izida: 2026
• Št. strani: 20 str.
• Številčenje: Vol. 14, art. 1761496
• PID: 20.500.12556/RUL-180257
• UDK: 591.5:612.43:504.5
• ISSN pri članku: 2296-665X
• DOI: 10.3389/fenvs.2026.1761496
• COBISS.SI-ID: 270421507
• Datum objave v RUL: 05.03.2026

Gradivo je del revije

• Naslov: Frontiers in environmental science
• Skrajšan naslov: Front. environ. sci.
• Založnik: Frontiers Media S.A.
• ISSN: 2296-665X
• COBISS.SI-ID: 523094297

Licence

• Licenca: CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by/4.0/deed.sl
• Opis: To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.

Sekundarni jezik

• Jezik: Slovenski jezik
• Ključne besede: ekosistemi, endokrine motnje, kemikalije, ki motijo ​​endokrini sistem, presnovne motnje, reproduktivne motnje, divji sesalci

Projekti

• Financer: ARIS - Javna agencija za znanstvenoraziskovalno in inovacijsko dejavnost Republike Slovenije
• Številka projekta: P4-0053-2019
• Naslov: Endokrini, imunski in encimski odzivi pri zdravih in bolnih živalih