Introduction: Foot pain presents a significant obstacle to performing daily activities. It can lead to poor balance and, consequently, injuries. Foot pain is associated with various pathologies and deformities, such as hallux valgus, Morton's neuroma, metatarsalgia, plantar fasciitis, heel spur, and others. Morton's neuroma, or interdigital neuroma, is a compressive neuropathy located between the second and third and/or third and fourth metatarsal heads. It most commonly occurs in women over the age of 50. The clinical presentation of Morton's neuroma includes a burning pain on the plantar side of the foot, that may radiate distally toward the toes, as well as tingling and numbness. The etiology of Morton's neuroma remains unclear and is based on symptoms, examination, and biomechanics. In the early stages of Morton's neuroma, treatment begins with replacing narrow footwear with comfortable shoes with a wide toe box. Custom-made orthopedic insoles, designed by an orthotist and prosthetist, have a beneficial effect on foot pain. They relieve painful areas, evenly distribute pressure across the foot while standing and walking, support the body, and reduce forces acting on the foot. Puprose: The aim of this thesis is to review professional and scientific literature to present the most optimal and effective orthotic treatment for patients with Morton's neuroma. Methods: A descriptive research method was used in this thesis, analyzing both foreign and domestic professional and scientific literature. Results: Eight studies were included in this research, examining the effectiveness of custom-made orthopedic insoles for patients with Morton's neuroma. The studies evaluated the effectiveness of orthopedic insoles in relieving foot pain and the efficiency of different materials used in their production. Some authors in the reviewed studies confirmed the effectiveness of orthopedic insoles in reducing pain associated with Morton's neuroma. Others stated that conservative treatment is more successful in patients with a shorter duration of symptoms. Some researchers suggested that surgical treatment should be considered if orthotic therapy proves ineffective. Additionally, research on materials used in orthopedic footwear indicated that thermoplastic and thermosetting polymers, foam plastics, and viscoelastic polymers are the most suitable materials. Discussion and conclusion: The characteristic pain in the forefoot is often disruptive in daily life and during many essential activities. Early recognition of the pathology and prompt intervention, particularly replacing narrow footwear, are crucial. If pain persists or the pathology is present for an extended period, treatment becomes more prolonged and requires consultation with an orthotist and prosthetist. In cases where conservative treatment fails, surgical intervention by an orthopedic specialist may be necessary.
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