Assessment of extracellular particles directly in plasma

Korenjak, Boštjan (avtor), Erjavec, Vladimira (avtor), Kralj-Iglič, Veronika (avtor)

Extracellular nanoparticles (EPs) in blood have been amply studied since their biological role was indicated more than 50 years ago. Among the various types of nano-sized blood constituents, the studies outlined lipoproteins, immune complexes and extracellular particles. Efforts have been invested to separate or separately assess different types of particles. Recently, much attention has been devoted to extracellular vesicles (EVs), however, experimental evidence indicates that the methods used for their harvesting and assessment importantly influence the content of the samples whereas the information on characteristics of the samples that could reflect the clinical status of the sample donor may be altered. Recent developments of the characterization methods point to the possibility of assessing nano-sized EPs directly in plasma and blood, thereby avoiding artefacts caused by processing. In this contribution, we consider the assessment of nano-sized EPs from blood and provide evidence supporting the direct assessment of EPs in plasma.

• Jezik: Angleški jezik
• Ključne besede: extracellular particles from blood, extracellular particles from plasma, interferometric light microscopy, dynamic light scattering
• Vrsta gradiva: Drugo
• Tipologija: 1.08 - Objavljeni znanstveni prispevek na konferenci
• Organizacija: ZF - Zdravstvena fakulteta ; VF - Veterinarska fakulteta
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Leto izida: 2024
• Št. strani: Str. 71-77
• PID: 20.500.12556/RUL-163378
• UDK: 577
• DOI: 10.55295/PSL.11.2024.8
• COBISS.SI-ID: 210329603
• Datum objave v RUL: 04.10.2024

Gradivo je del monografije

• Naslov: Socratic Lectures : 11th international symposium, Ljubljana, 8. June 2024
• Uredniki: Veronika Kralj-Iglič, Yelena Istileulova, Anna Romolo
• Kraj izida: Ljubljana
• Založnik: University of Ljubljana Press
• Leto izida: 2024
• ISBN: 978-961-297-383-4
• COBISS.SI-ID: 205044227

Licence

• Licenca: CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by/4.0/deed.sl
• Opis: To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.

Projekti

• Financer: ARIS - Javna agencija za znanstvenoraziskovalno in inovacijsko dejavnost Republike Slovenije
• Številka projekta: J3-3066-2021
• Naslov: Optimizacija s trombociti in zunajceličnimi vezikli bogate avtologne krvne plazme za zdravljenje pooperativnih ran v otorinolaringologiji

• Financer: ARIS - Javna agencija za znanstvenoraziskovalno in inovacijsko dejavnost Republike Slovenije
• Številka projekta: P3-0388-2022
• Naslov: Mehanizmi varovanja zdravja