Enaminones are compounds containing an amino group conjugated with a carbonyl group via a C=C double bond. Enaminones are of great importance in synthetic organic chemistry, since they can be used in the syntheses of various heterocyclic systems. Reactions of enaminones usually take place under mild reaction conditions and the products are obtained in good yields. Previously, enaminones were usually synthesised by the condensation reactions between ketones and amines or by addition reactions between amines and electron-deficient alkynes (ynones). Today, new synthetic methods with an emphasis on green chemistry principles are increasingly investigated. In this thesis we have attempted to synthesise two enaminones, ethyl (E)-3-(phenylamino)acrylate (75) and ethyl (E)-3-(allylamino)acrylate (73), via a modified literature procedure following the principles of green chemistry. We performed non-catalysed Michael addition reactions of aniline and allylamine to ethyl propiolate at room temperature, under solvent-free reaction conditions. Next, the amine groups of the synthesised enaminones were protected using Boc2O as the reagent.
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