Reproductive outcomes after laparoscopic surgery in infertile women affected by ovarian endometriomas, with or without in vitro fertilisation : results from the SAFE (surgery and ART for endometriomas) trial

Ban, Helena (avtor), Vrtačnik-Bokal, Eda (avtor), Štimpfel, Martin (avtor), Divjak Budihna, Teja (avtor), Gulino, Ferdinando Antonio (avtor), Garzon, Simone (avtor), Ghezzi, Fabio (avtor), Alkatout, Ibrahim (avtor), Gitas, Georgios (avtor), Laganà, Antonio Simone (avtor)

We performed a retrospective cohort study, namely “Surgery and ART for Endometriomas” (SAFE) trial (Clinical Trial ID: NCT03717870), including women who underwent laparoscopic cystectomy for endometrioma before first IVF and compared their reproductive outcomes with the ones of women without endometriosis and with unexplained infertility, tubal factor or male factor infertility. We found that women who underwent previous laparoscopic cystectomy for endometrioma had higher FSH and LH levels between the 2nd and 5th day of the cycle before IVF, required higher doses of gonadotrophins for ovarian stimulation and had a lower number of retrieved oocytes compared with other types of infertility. Nevertheless, pregnancy and delivery rates remain comparable to other causes of infertility. In addition, differences in ovarian stimulation parameters between endometriosis and other types of infertility lost significance with the increase of women’s age. These pieces of information can be considered useful to make adequate counselling about reproductive outcomes for infertile women with ovarian endometriomas and allow a proper decision-making approach shared with the patient.

• Jezik: Angleški jezik
• Ključne besede: endometriosis, laparoscopic surgery, in vitro fertilisation, reproductive outcomes
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.01 - Izvirni znanstveni članek
• Organizacija: MF - Medicinska fakulteta
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Leto izida: 2022
• Št. strani: Str. 1293-1300
• Številčenje: Vol. 42, no. 5
• PID: 20.500.12556/RUL-141233
• UDK: 618.1
• ISSN pri članku: 0144-3615
• DOI: 10.1080/01443615.2021.1959536
• COBISS.SI-ID: 95982595
• Datum objave v RUL: 26.09.2022

Gradivo je del revije

• Naslov: Journal of obstetrics and gynaecology
• Skrajšan naslov: J. obstet. gynaecol.
• Založnik: Taylor & Francis
• ISSN: 0144-3615
• COBISS.SI-ID: 738325

Licence

• Licenca: CC BY-NC-ND 4.0, Creative Commons Priznanje avtorstva-Nekomercialno-Brez predelav 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by-nc-nd/4.0/deed.sl
• Opis: Najbolj omejujoča licenca Creative Commons. Uporabniki lahko prenesejo in delijo delo v nekomercialne namene in ga ne smejo uporabiti za nobene druge namene.

Sekundarni jezik

• Jezik: Slovenski jezik
• Ključne besede: ginekologija, laparoskopska kirurgija, neplodnost, endometrioza