Click chemistry is one of the newer methods of organic synthesis, where new compounds with C–X–C bonds are synthesized. For a reaction to be defined as click chemistry, certain conditions must be met. One of the most important reactions in click chemistry is 1,3-dipolar cycloaddition, which is a pericyclic reaction and is used to synthesize heterocyclic systems with an odd number of atoms in the ring. In addition, in the introduction I focused on azomethine imines, which are involved in the synthesis of wide variety of heterocycles. The last part of the introduction describes bicyclic pyrazolidinones.
The experimental part of the thesis includes the synthesis of azomethine imines from 3-pyrazolidinones and the 1,3-dipolar cycloaddition of azomethine imines to terminal alkynes for the synthesis of pyrazolo[1,2-a]pyrazoles.
|