New insights into antibacterial and antifungal properties, cytotoxicity and aquatic ecotoxicity of flame retardant PA6/DOPO-derivative nanocomposite textile fibers

Vasiljević, Jelena (avtor), Štular, Danaja (avtor), Kalčíková, Gabriela (avtor), Zajc, Janja (avtor), Šobak, Matic (avtor), Demšar, Andrej (avtor), Tomšič, Brigita (avtor), Simončič, Barbara (avtor), Čolović, Marija (avtor), Šelih, Vid Simon (avtor), Jerman, Ivan (avtor)

The aim of this study was to evaluate the antibacterial and antifungal activity, cytotoxicity, leaching, and ecotoxicity of novel flame retardant polyamide 6 (PA6) textile fibers developed by our research group. The textile fibers were produced by the incorporation of flame-retardant bridged 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide (DOPO) derivative (PHED) in the PA6 matrix during the in situ polymerization process at concentrations equal to 10 and 15 wt% (PA6/10PHED and PA6/15PHED, respectively). Whilst the nanodispersed PHED provided highly efficient flame retardancy, its biological activity led to excellent antibacterial activity against Escherichia coli and Staphylococcus aureus, as well as excellent antifungal activity against Aspergillus niger and Candida albicans. The results confirmed leaching of the PHED, but the tested leachates did not cause any measurable toxic effect to the duckweed Lemna minor. The in vitro cytotoxicity of the leached PHED from the PA6/15PHED sample was confirmed for human cells from adipose tissue in direct and prolonged contact. The targeted biological activity of the organophosphinate flame retardant could be beneficial for the development of PA6 textile materials with multifunctional properties and the low ecotoxicity profile, while the PHED’s leaching and cytotoxicity limit their application involving the washing processes and direct contact with the skin.

• Jezik: Angleški jezik
• Ključne besede: polyamide 6, textile filament, DOPO derivative, antibacterial activity, antifungal activity, ecotoxicity, cytotoxicity
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.01 - Izvirni znanstveni članek
• Organizacija: NTF - Naravoslovnotehniška fakulteta ; FKKT - Fakulteta za kemijo in kemijsko tehnologijo
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Leto izida: 2021
• Št. strani: 17 str.
• Številčenje: Vol. 13, iss. 6, art. 905
• PID: 20.500.12556/RUL-135199
• UDK: 677
• ISSN pri članku: 2073-4360
• DOI: 10.3390/polym13060905
• COBISS.SI-ID: 55570947
• Datum objave v RUL: 28.02.2022

Gradivo je del revije

• Naslov: Polymers
• Skrajšan naslov: Polymers
• Založnik: Molecular Diversity Preservation International
• ISSN: 2073-4360
• COBISS.SI-ID: 517951257

Licence

• Licenca: CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by/4.0/deed.sl
• Opis: To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.
• Začetek licenciranja: 15.03.2021

Sekundarni jezik

• Jezik: Slovenski jezik
• Ključne besede: poliamid 6, tekstilni filament, DOPO derivat, antibakterijsko delovanje, protiglivično delovanje, ekotoksičnost, citotoksičnost