Effectiveness of ultrasound-guided canal adductor blockade for chronic pain and functioning in knee osteoarthritis : a prospective longitudinal observational study

Salihović, Mensur (avtor), Rijavec, Boris (avtor), Muratagić, Anida (avtor), Blagus, Rok (avtor), Puh, Urška (avtor)

Background and Objective. Knee osteoarthritis is a serious epidemiological problem that causes severe pain and impairs abilities. We investigated the effects of adductor canal blockade (ACB) on chronic osteoarthritis knee pain, motor function, and mobility. Methods. Seventy-seven patients with chronic knee osteoarthritis pain received ultrasound-guided ACB with 14 ml 0.25% levobupivacaine and 100 mcg clonidine. At baseline and 1 month after the blockade, we assessed maximal and minimal pain intensity in the knee using a numeric rating scale (NRS) and the Knee Injury and Osteoarthritis Outcome Score (KOOS). The range of motion in extension and flexion (ROMext and ROMflex) and quadriceps muscle strength of both knees (QS), Timed Up and Go Test (TUG), and 30-Second Chair Stand Test (30CST) results were determined at baseline, 1 hour, 1 week, and 1 month after the blockade. Results. ACB with levobupivacaine and clonidine appeared to decrease pain severity ( 8.13 to 4.2, and 3.32 to 1.40, ). Similarly, knee ROMext decreased from 3.90 preintervention to 2.89 postintervention at 1 month, ; ROMflex decreased from 5.70 to 3.29, ; TUG time decreased from 3.22 to 2.93, <0.001; QS increased from 18.43 to 22.77, ; CST increased from 8.23 to 10.74, . The KOOS for pain (36.40 to 58.34), symptoms (52.55 to 64.32), activities of daily living functions (ADLs, 36.36 to 60.77), and quality of life (QoL, 17.87 to 30.97) also increased, all . Conclusion. ACB appeared to decrease pain and increase ambulation. If our preliminary results are reproducible in a planned randomized controlled trial, ACB could be a useful adjunctive pain therapy in patients with disabling pain due to knee OA.

• Jezik: Angleški jezik
• Ključne besede: osteoarthritis, knee, ultrasound-guided canal blockade
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.01 - Izvirni znanstveni članek
• Organizacija: MF - Medicinska fakulteta ; ZF - Zdravstvena fakulteta
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Poslano v recenzijo: 22.07.2021
• Datum sprejetja članka: 01.12.2021
• Datum objave: 22.01.2022
• Leto izida: 2022
• Št. strani: Str. 1-10
• Številčenje: Vol. 2022
• PID: 20.500.12556/RUL-134795
• UDK: 615.82/.84
• ISSN pri članku: 2314-6141
• DOI: 10.1155/2022/5270662
• COBISS.SI-ID: 94589699
• Datum objave v RUL: 02.02.2022

Gradivo je del revije

• Naslov: BioMed research international
• Skrajšan naslov: Biomed Res Int
• Založnik: Hindawi Publishing
• ISSN: 2314-6141
• COBISS.SI-ID: 30624729

Licence

• Licenca: CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by/4.0/deed.sl
• Opis: To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.
• Začetek licenciranja: 22.01.2022

Sekundarni jezik

• Jezik: Ni določen
• Ključne besede: osteoartritis, koleno, blokada kanala z ultrazvočnim vodenjem, zdravila