Uric acid and plant-based nutrition

Jakše, Boštjan (avtor), Jakše, Barbara (avtor), Pajek, Maja (avtor), Pajek, Jernej (avtor)

Plant-based diets (PBDs) are associated with decreased risk of morbidity and mortality associated with important noncommunicable chronic diseases. Similar to animal-based food sources (e.g., meat, fish, and animal visceral organs), some plant-based food sources (e.g., certain soy legume products, sea vegetables, and brassica vegetables) also contain a high purine load. Suboptimally designed PBDs might consequently be associated with increased uric acid levels and gout development. Here, we review the available data on this topic, with a great majority of studies showing reduced risk of hyperuricemia and gout with vegetarian (especially lacto-vegetarian) PBDs. Additionally, type of ingested purines, fiber, vitamin C, and certain lifestyle factors work in concordance to reduce uric acid generation in PBDs. Recent limited data show that even with an exclusive PBD, uric acid concentrations remain in the normal range in short- and long-term dieters. The reasonable consumption of plant foods with a higher purine content as a part of PBDs may therefore be safely tolerated in normouricemic individuals, but additional data is needed in hyperuricemic individuals, especially those with chronic kidney disease.

• Jezik: Angleški jezik
• Ključne besede: uric acid, plant-based diets, chronic diseases, purine, hyperuricemia, gout
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.02 - Pregledni znanstveni članek
• Organizacija: BF - Biotehniška fakulteta ; FŠ - Fakulteta za šport
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Leto izida: 2019
• Št. strani: 15 str.
• Številčenje: Vol. 11, iss. 8, art. 1736
• PID: 20.500.12556/RUL-132827
• UDK: 616.6
• ISSN pri članku: 2072-6643
• DOI: 10.3390/nu11081736
• COBISS.SI-ID: 6381484
• Datum objave v RUL: 04.11.2021

Gradivo je del revije

• Naslov: Nutrients
• Skrajšan naslov: Nutrients
• Založnik: MDPI
• ISSN: 2072-6643
• COBISS.SI-ID: 2948140

Licence

• Licenca: CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by/4.0/deed.sl
• Opis: To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.
• Začetek licenciranja: 01.08.2019

Projekti

• Financer: ARRS - Agencija za raziskovalno dejavnost Republike Slovenije
• Številka projekta: P3-0323
• Naslov: Ledvične bolezni in nadomestna zdravljenja