This diploma thesis describes attempts to prepare some of ester derivatives of pyruvic acid and its analogue, bromopyruvic acid, as well as an attempt to synthesize bromopyruvic acid itself. Transformations of pyruvic acid into its cyclohexyl ester and lactic acid into methyl lactate were successful. Bromination of allyl and propargyl esters of pyruvic acid (prepared successfully, albeit in a low yield only) that should provide 2,3-dibromopropyl pyruvate and 2,2,3,3-tetrabromopropyl pyruvate, on the other hand, took place only partially and the results were somewhat below those expected, as the yields were low or the products identities could not be unequivocally confirmed. All reactions were performed completely or partially according to the procedures published in the literature. Final and intermediate products were characterised using 1H NMR spectroscopy, IR spectroscopy, and HRMS.
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